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精准医学：胃癌个体化治疗信息分析与知识发现
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检索分析系统
研究论文175篇分布如下
publications over time
知识发现结果如下
http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi
A-query: stomach cancer
C-query: individualized therapy
The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 175 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 6088 and can be accessed from the start page after you leave this session. There are 1292 terms on the current B-list (415 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin.
To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.
job id # 6088 started Sun May 17 18:37:25 2015
Max_citations: 50000
Stoplist: /var/www/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
A_query_raw: stomach cancer Sun May 17 18:37:33 2015
A query = stomach cancer started Sun May 17 18:37:34 2015
A query resulted in 50000 titles
C_query_raw: individualized therapy Sun May 17 18:37:46 2015
C: individualized therapy 23879
A: stomach cancer 92576
AC: ( stomach cancer ) AND ( individualized therapy ) 175
C_query_raw: individualized therapy Sun May 17 18:37:51 2015
C: individualized therapy 23879
A: stomach cancer 92576
AC: ( stomach cancer ) AND ( individualized therapy ) 175
C query = individualized therapy started Sun May 17 18:37:51 2015
C query resulted in 23879 titles
A AND C query resulted in 175 titles
26071 B-terms ready on Sun May 17 18:40:57 2015
Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
1292 B-terms left after filter executed Sun May 17 18:43:19 2015
B-list on Sun May 17 18:48:18 2015
1 brca2
2 adiponectin
3 brca1
4 promoter polymorphism
5 cyp2c19
6 cyp2d6
7 akt
8 vegf
9 mthfr
10 nat2
11 k ras
12 single nucleotide polymorphism
13 mtor
14 fdg
15 stat3
16 cox-2
17 her-2 neu
18 toll receptor
19 tp53
20 braf
21 pi3k
22 her2
23 gstp1
24 herg
25 pten
26 her-2
27 cancer gene expression
28 ugt1a1
29 notch1
30 dpyd
31 dihydropyrimidine dehydrogenase
32 promotor polymorphism
33 cyp2a6
34 microsatellite
35 cytokine gene
36 ppargamma
37 dota
38 mdr1
39 multiple endocrine neoplasia
40 microrna
41 promoter methylation
42 tnm
43 gene promoter polymorphism
44 ercc1
45 dihydropyrimidine dehydrogenase gene
46 statin
47 cd133
48 gene promoter
49 beta catenin
50 cyclin e
| AB literature
| B-term
| BC literature
|
| stomach cancer | brca2 | individualized therapy |
| 1: [Genetic counselling in male carriers of BRCA1 and BRCA2 gene mutations]. 2012 Add to clipboard 2: A case of familial breast cancer with double heterozygosity for BRCA1 and BRCA2 genes. 2012 3: BRCA1 and BRCA2 mutations among familial breast cancer patients from Costa Rica. 2011 4: Risk of cancer other than breast or ovarian in individuals with BRCA1 and BRCA2 mutations. 2011 5: Cancer prevalence in 129 breast-ovarian cancer families tested for BRCA1 and BRCA2 mutations. 2010 6: The prevalence of BRCA1 and BRCA2 germline mutations in high-risk breast cancer patients of Chinese Han nationality: two recurrent mutations were identified. 2008 7: Incidence of BRCA1 and BRCA2 mutations in 54 Chilean families with breast/ovarian cancer, genotype-phenotype correlations. 2006 8: Spontaneous and irradiation-induced tumor susceptibility in BRCA2 germline mutant mice and cooperative effects with a p53 germline mutation. 2006 9: BRCA1 and BRCA2 pathways and the risk of cancers other than breast or ovarian. 2005 10: Cancer risks for male carriers of germline mutations in BRCA1 or BRCA2: a review of the literature. 2004 11: Cancer variation associated with the position of the mutation in the BRCA2 gene. 2004 12: No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer. 2004 13: Risk of cancer at sites other than the breast in Swedish families eligible for BRCA1 or BRCA2 mutation testing. 2004 14: A high frequency of BRCA2 gene mutations in Polish families with ovarian and stomach cancer. 2003 15: The effect of a single BRCA2 mutation on cancer in Iceland. 2002 16:BRCA2 gene mutations in families with aggregations of breast and stomach cancers. 2002 17: Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer. 2001 18: Cancer risks in BRCA2 mutation carriers. The Breast Cancer Linkage Consortium. 1999 19: Incidence of malignant tumours in relatives of BRCA1 and BRCA2 germline mutation carriers. 1999 20: A common mutation in BRCA2 that predisposes to a variety of cancers is found in both Jewish Ashkenazi and non-Jewish individuals. 1996
| 1: In Brief: BRCA1 and BRCA2. 2013 Add to clipboard 2: BRCA1 and BRCA2 mutations and breast cancer. 2011 3: Contralateral breast cancer in BRCA1/BRCA2 mutation carriers: the story of the other side. 2009 4: Targeting Fanconi anemia/BRCA2 pathway defects in cancer: the significance of preclinical pharmacogenomic models. 2007 5: [Hereditary breast and ovarian cancer: primary and secondary prevention for BRCA1 and BRCA2 mutation carriers] 2007 6: Bilateral risk-reducing oophorectomy in BRCA1 and BRCA2 mutation carriers. 2006
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http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi
https://wap.sciencenet.cn/blog-280034-890937.html
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