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顶级生物学论文 TOP 10 OF BIOLOGY 17 August 2010

已有 4540 次阅读 2010-8-17 08:48 |个人分类:生物科学|系统分类:论文交流| 论文, 生物学, biology, Top

http://f1000biology.com/top10/jewels


1
Exceptional
F1000 Factor 9.9

Hypothesis
New Finding
Novel Drug Target
 Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARgamma by Cdk5.
Choi JH, Banks AS, …, Griffin PR, Spiegelman BM
Nature 2010 Jul 22 466(7305):451-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Lawrence Hamann / Michael Andresen / Paul Webb
First evaluation 23 Jul 2010 | Latest evaluation 16 Aug 2010
 
2
Exceptional
F1000 Factor 9.6

Hypothesis
New Finding
Novel Drug Target
 Branched tricarboxylic acid metabolism in Plasmodium falciparum.
Olszewski KL, Mather MW, …, Rabinowitz JD, Llinás M
Nature 2010 Aug 5 466(7307):774-8 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Paul Roepe / Robert Abraham
Evaluated 11 Aug 2010
 
3
Exceptional
F1000 Factor 8.0

New Finding
 Activity-Dependent Expression of Lmx1b Regulates Specification of Serotonergic Neurons Modulating Swimming Behavior.
Demarque M, Spitzer NC
Neuron 2010 Jul 29 67(2):321-334 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Keith Sillar / Judith S Eisen
First evaluation 4 Aug 2010 | Latest evaluation 5 Aug 2010
 
4
Exceptional
F1000 Factor 8.0

New Finding
 Melanopsin-expressing retinal ganglion-cell photoreceptors: cellular diversity and role in pattern vision.
Ecker JL, Dumitrescu ON, …, Berson DM, Hattar S
Neuron 2010 Jul 15 67(1):49-60 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Roger Hardie / Steven Reppert
First evaluation 26 Jul 2010 | Latest evaluation 4 Aug 2010
 
5
Must Read
F1000 Factor 7.2

New Finding
Tech Advance
 Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics.
Grashoff C, Hoffman BD, …, Ha T, Schwartz MA
Nature 2010 Jul 8 466(7303):263-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Harold Erickson / Vivian Tang / Mark Morgan and Martin Humphries / Jan Lammerding / Madhavi Maddugoda and Alpha Yap / Donna Webb
First evaluation 27 Jul 2010 | Latest evaluation 16 Aug 2010
 
6
Must Read
F1000 Factor 7.2

Confirmation
Hypothesis
New Finding
 A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution.
Hu Q, Milenkovic L, …, Spiliotis ET, Nelson WJ
Science 2010 Jul 23 329(5990):436-9 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Yves Barral / Maureen Wirschell and Winfield Sale / Heike Folsch / Yukiko Yamashita / Monica Bettencourt-Dias / Shanshan Feng and Wei Guo
First evaluation 19 Jul 2010 | Latest evaluation 11 Aug 2010
 
7
Must Read
F1000 Factor 6.5

Hypothesis
New Finding
Tech Advance
 Microtubule nucleating gamma-TuSC assembles structures with 13-fold microtubule-like symmetry.
Kollman JM, Polka JK, …, Davis TN, Agard DA
Nature 2010 Aug 12 466(7308):879-82 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Edward Egelman / Hong-Wei Wang / Linda Amos
First evaluation 29 Jul 2010 | Latest evaluation 16 Aug 2010
 
8
Must Read
F1000 Factor 6.5

Confirmation
Hypothesis
New Finding
 Identification of the switch in early-to-late endosome transition.
Poteryaev D, Datta S, …, Zerial M, Spang A
Cell 2010 Apr 30 141(3):497-508 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Pamela Vanderzalm and Richard Fehon / Yue Sun and Richard Anderson / Jordan Wesolowski and Fabienne Paumet
First evaluation 13 Jul 2010 | Latest evaluation 11 Aug 2010
 
9
Must Read
F1000 Factor 6.4

Confirmation
New Finding
Tech Advance
 C. elegans TRP Family Protein TRP-4 Is a Pore-Forming Subunit of a Native Mechanotransduction Channel.
Kang L, Gao J, …, Xie Z, Xu XZ
Neuron 2010 Aug 12 67(3):381-391 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | Roger Hardie / Paul Garrity
First evaluation 13 Aug 2010 | Latest evaluation 16 Aug 2010
 
10
Must Read
F1000 Factor 6.4

New Finding
Novel Drug Target
 Staphylococcus aureus nonribosomal peptide secondary metabolites regulate virulence.
Wyatt MA, Wang W, …, Dunman PM, Magarvey NA
Science 2010 Jul 16 329(5989):294-6 [abstract on PubMed] [related articles] [full text] [order article]
Selected by | R Kip Guy / Mary Elizabeth Shillito and Sheryl Tsai
First evaluation 29 Jul 2010 | Latest evaluation 13 Aug 2010

Top 10s are generated every day using only papers added to F1000 Biology over the preceding month. Papers are ranked according to their F1000 Factor which incorporates both the number of times a paper has been evaluated, and the ratings it received. If any papers have an equal F1000 Factor then the most recently added paper is listed first.



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