#编者信息

熊荣川

六盘水师范学院生物信息学实验室

明湖实验室

xiongrongchuan@126.com

http://blog.sciencenet.cn/u/Bearjazz

1、MEGA: MolecularEvolutionary Genetics Analysis

MEGA is an integrated tool for automaticand manual sequence alignment,

inferring phylogenetic trees, miningweb-based databases, estimating rates

of molecular evolution, and testingevolutionary hypotheses.

2、Bioedit

序列编辑器与分析工具软件。功能包括：序列编辑、外挂分析程序、RNA分析、寻找特征序列、支持超过20000个序列的多序列文件、基本序列处理功能、质粒图绘制等等。

3、TCS

TCS is a computer program that implementsthe estimation of gene genealogies from DNA

sequences as described by (Templeton et al.1992). This cladogram estimation method is also

known as statistical parsimony.

4、GeoDis

GeoDis: a program for the cladistic nested analysisof the geographical distribution of genetic haplotypes

5、Migrate

Maximum-likelihoodestimation of migration rates and population numbers of two populations using acoalescent approach. Genetics 152:763–773.

http://evolution.genetics.washington.edu/lamarc/index.html

6、LAMARC

LAMARC is a program which estimatespopulation-genetic parameters such as population size, population growth rate,recombination rate, and migration rates. It approximates a summation over allpossible genealogies that could explain the observed sample, which may besequence, SNP, microsatellite, or electrophoretic data. LAMARC and its sisterprogram Migrate are successor programs to the older programs Coalesce,Fluctuate, and Recombine, which are no longer being supported. The programs arememory-intensive but can run effectively on workstations; we support a varietyof operating systems.

http://evolution.genetics.washington.edu/lamarc/index.html