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糖尿病与睡眠的基因知识发现与信息分析

已有 1701 次阅读 2015-4-29 10:26 |个人分类:信息分析|系统分类:科研笔记

最新研究动态

糖尿病会降低睡眠质量

 

日本大阪市立大学教授稻叶雅章率领的研究小组在新一期美国《科学公共图书馆综合卷》上报告说,他们通过脑电图仪检测,证实糖尿病患者的血糖控制情况恶化,血糖值上升后,睡眠质量也会随之降低。

 

http://paper.sciencenet.cn/htmlpaper/20154281016646636220.shtm


A-query: type-2 diabetes mellitus
C-query: sleep quality

The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 121 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 11044 and can be accessed from the start page after you leave this session. There are 697 terms on the current B-list (131 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin.

To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

 

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

 

job id # 11044 started Tue Apr 28 21:12:22 2015
Max_citations: 50000
Stoplist: /var/www/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
A_query_raw: type-2 diabetes mellitus Tue Apr 28 21:12:31 2015

A query = type-2 diabetes mellitus started Tue Apr 28 21:12:32 2015
A query resulted in 50000 titles
C_query_raw: sleep quality Tue Apr 28 21:12:44 2015

C: sleep quality 16617

A: type-2 diabetes mellitus 97432

AC: ( type-2 diabetes mellitus ) AND ( sleep quality ) 121

C_query_raw: sleep quality Tue Apr 28 21:12:49 2015

C: sleep quality 16617

A: type-2 diabetes mellitus 97432

AC: ( type-2 diabetes mellitus ) AND ( sleep quality ) 121

C query = sleep quality started Tue Apr 28 21:12:49 2015
C query resulted in 16617 titles
A AND C query resulted in 121 titles
21778 B-terms ready on Tue Apr 28 21:15:32 2015

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
697 B-terms left after filter executed Tue Apr 28 21:20:29 2015

B-list on Tue Apr 28 21:24:54 2015
1 adiponectin
2 clock gene
3 ghrelin
4 leptin
5 single nucleotide polymorphism
6 fat mass
7 statin
8 angiotensin receptor
9 rct
10 cpap
11 metabolic syndrome
12 body mass index
13 cyp2c19
14 il-6
15 bone mineral density
16 ace gene
17 polycystic ovary syndrome
18 genome wide
19 adiposity
20 sglt2
21 estrogen receptor beta
22 rem
23 fasting glucose
24 pcos
25 copd
26 bdnf
27 snp
28 chi
29 microrna
30 tnf alpha
31 igf-1
32 bmal1
33 gene environment
34 trpv1
35 body mass
36 hpa
37 apoe
38 serotonin transporter gene
39 cytokine production
40 cbt
41 lean
42 cyp2d6
43 tnf
44 cytokine
45 ace
46 per3
47 inflammatory cytokine gene
48 sms
49 gene promoter
50 association ace gene
51 hyperlipidemia
52 insulin level
53 transporter gene
54 diabetes mellitus
55 platelet activation
56 enzyme gene
57 clock
58 diabetic nephropathy
59 il-10
60 th1
61 xr
62 transporter
63 renin
64 app
65 race
66 circadian clock gene
67 hyperparathyroidism
68 carpal tunnel syndrome
69 gad
70 yoga
71 circadian rhythm
72 casein kinase
73 obese
74 aromatase
75 arab
76 han
77 cytokine gene
78 5-ht2a
79 atherosclerosis
80 tea
81 rest
82 diabetes
83 apolipoprotein e
84 alzheimer disease
85 anxiety
86 dream
87 tai
88 erp
89 systolic blood pressure
90 sequencing gene
91 db
92 interleukin
93 bypass
94 tsh
95 obesity
96 hmg coa reductase
97 asia
98 mph
99 estrogen receptor
100 body weight
101 crp
102 trait
103 capd
104 nse
105 parkinson disease
106 calcium channel
107 hemoglobin
108 interleukin receptor
109 lipocalin
110 ga
111 fat
112 vitamin e c
113 pen
114 blind
115 prostate cancer
116 meta
117 heparanase
118 en
119 alcohol withdrawal
120 inflammatory bowel disease
121 add
122 flash
123 hip
124 igf1
125 gonadotropin releasing hormone
126 icf
127 cholesterol
128 cgmp
129 receptor gene
130 insulin
131 erythropoietin

 


字段:年份 趋势图
记录数
占%
 01.2015     1 0.826%
 02.2014     16 13.223%
 03.2013     23 19.008%
 04.2012     13 10.744%
 05.2011     7 5.785%
 06.2010     11 9.091%
 07.2009     10 8.264%
 08.2008     9 7.438%
 09.2005     5 4.132%
 10.2003     3 2.479%
查看更多
字段:期刊
记录数
占%
 01.diabetes care     6 4.959%
 02.diabetes educ     5 4.132%
 03.diabet med     3 2.479%
 04.diabetes metab     3 2.479%
 05.diabetes res clin pract     3 2.479%
 06.sleep med     3 2.479%
 07.clin cornerstone     2 1.653%
 08.drugs     2 1.653%
 09.front horm res     2 1.653%
字段:中国大陆外机构
记录数
占%
 01.芝加哥大学     6 4.959%
 02.匹兹堡大学     4 3.306%
 03.约翰霍普金斯大学     4 3.306%
 04.加州大学     3 2.479%
 05.约翰霍普金斯大学医学院     3 2.479%
 06.哈佛医学院     2 1.653%
 07.哈佛大学公共健康学院     2 1.653%
 08.哥伦比亚大学     2 1.653%
 09.布莱根妇女医院     2 1.653%
 10.斯坦福大学     2 1.653%
查看更多
字段:中国大陆单位
记录数
占%
 01.河北医科大学校本部     1 0.826%
 02.浙江大学医学院附属第二医院     1 0.826%
 03.浙江省人民医院(浙江省立医院)     1 0.826%
 04.皖南医学院校本部     1 0.826%
查看更多
字段:中国作者
记录数
占%
 01.河北医科大学校本部.刘殿武     1 0.826%
 02.河北医科大学校本部.唐龙妹     1 0.826%
 03.浙江大学医学院附属第二医院.禹华良     1 0.826%
 04.浙江大学医学院附属第二医院.陈怀红     1 0.826%
 05.浙江省人民医院(浙江省立医院).华燕吟     1 0.826%
 06.浙江省人民医院(浙江省立医院).叶乐勤     1 0.826%
 07.浙江省人民医院(浙江省立医院).宋迎香     1 0.826%
 08.皖南医学院校本部.姚应水     1 0.826%
 09.皖南医学院校本部.金岳龙     1 0.826%
 10.皖南医学院校本部.陈燕     1 0.826%
查看更多
字段:作者缩写
记录数
占%
 01.Punjabi NM     5 4.132%
 02.Van Cauter E     5 4.132%
 03.Chasens ER     4 3.306%
 04.Leproult R     4 3.306%
 05.Brod M     3 2.479%
 06.Burke LE     3 2.479%
 07.Christensen T     3 2.479%
 08.Knutson KL     3 2.479%
 09.Korytkowski M     3 2.479%
 10.Li Z     3 2.479%
查看更多
字段:文献主题词 趋势图
记录数
占%
 01.diabetes mellitus, type 2     64 52.893%
 02.quality of life     29 23.967%
 03.obesity     26 21.488%
 04.risk factors     24 19.835%
 05.hypertension     20 16.529%
 06.sleep disorders     20 16.529%
 07.body mass index     19 15.702%
 08.questionnaires     17 14.050%
 09.sleep     17 14.050%
 10.cross-sectional studies     16 13.223%
查看更多
字段:副主题词搭配 趋势图
记录数
占%
 03.Hypertension/epidemiology     11 9.091%
 04.Obesity, Morbid/surgery*     11 9.091%
 06.Obesity/epidemiology     10 8.264%
 07.Quality of Life*     10 8.264%
 08.Sleep Disorders/epidemiology     9 7.438%
查看更多
字段:国家 分布图
记录数
占%
 01.美国     45 37.190%
 02.法国     7 5.785%
 03.中国大陆     6 4.959%
 04.日本     6 4.959%
 05.巴西     5 4.132%
 06.澳大利亚     5 4.132%
 07.德国     4 3.306%
 08.意大利     4 3.306%
 09.英国     4 3.306%
 10.韩国     4 3.306%
查看更多
字段:城市
记录数
占%
 01.美国芝加哥     9 7.438%
 02.美国波士顿     6 4.959%
 03.美国匹兹堡     5 4.132%
 04.美国巴的摩尔     5 4.132%
 05.美国巴尔的摩霍普金斯     4 3.306%
 06.澳大利亚墨尔本     3 2.479%
 07.fortaleza     2 1.653%
 08.victoria.au     2 1.653%
 09.比利时布鲁塞尔     2 1.653%
 10.法国巴黎     2 1.653%
查看更多
字段:中国省份 分布图
记录数
占%
 01.台湾     2 1.653%
 02.浙江省     2 1.653%
 03.天津     1 0.826%
 04.安徽省     1 0.826%
 05.河北省     1 0.826%
字段:药物
记录数
占%
 01.insulin     41 33.884%
 02.blood glucose     16 13.223%
 03.hemoglobin a, glycosylated     15 12.397%
 04.globins     12 9.917%
 05.hemoglobin a     12 9.917%
 06.hemoglobins     12 9.917%
 07.cholesterol     8 6.612%
 08.pancreatic hormones     7 5.785%
 09.insulins     6 4.959%
 10.proinsulin     6 4.959%
查看更多
字段:Substance
记录数
占%
 01.blood glucose     9 7.438%
 02.hemoglobin a, glycosylated     8 6.612%
 03.glucose     5 4.132%
 04.hypoglycemic agents     4 3.306%
 05.insulin     3 2.479%
 06.amyloid     2 1.653%
 07.anticonvulsants     2 1.653%
 08.antidepressive agents     2 1.653%
 09.hemoglobin a1c protein, human     2 1.653%
 10.islet amyloid polypeptide     2 1.653%
查看更多
没有聚类出数据
字段:疾病
记录数
占%
 01.糖尿病     117 96.694%
 02.2型糖尿病     116 95.868%
 03.营养与代谢疾病     100 82.645%
 04.代谢疾病     97 80.165%
 05.葡萄糖代谢障碍     95 78.512%
 06.内分泌系统疾病     94 77.686%
 07.睡眠障碍     69 57.025%
 08.神经系统疾病     69 57.025%
 09.肥胖症     56 46.281%
 10.睡眠呼吸暂停综合征     49 40.496%
查看更多
字段:症状
记录数
占%
 01.睡眠障碍     66 54.545%
 02.肥胖症     54 44.628%
 03.体重     50 41.322%
 04.超重     50 41.322%
 05.呼吸暂停     47 38.843%
 06.sleep disturbances     27 22.314%
 07.体重减轻     23 19.008%
 08.综合征     23 19.008%
 09.sleep difficult     21 17.355%
 10.疼痛     17 14.050%
查看更多
字段:治疗方法
记录数
占%
 01.心理生理学     38 31.405%
 02.肥胖治疗外科     22 18.182%
 03.外科手术     20 16.529%
 04.超体重学,肥胖症治疗学     19 15.702%
 05.消化系统外科手术     14 11.570%
 06.胃旁路术     11 9.091%
 07.康复     10 8.264%
 08.自我护理     8 6.612%
 09.外科吻合术     7 5.785%
 10.胃成形术     7 5.785%
查看更多
字段:科室
记录数
占%
 01.department of medicine     8 6.612%
 02.school of medicine     7 5.785%
 03.department of internal medicine     5 4.132%
 04.department of endocrinology     3 2.479%
 05.department of surgery     3 2.479%
 06.beth israel deaconess medical center     2 1.653%
 07.college of medicine     2 1.653%
 08.college of physicians and surgeons     2 1.653%
 09.department of epidemiology and statistics     2 1.653%
 10.department of neurology     2 1.653%
查看更多
字段:物种
记录数
占%
 01.animals     105 86.777%
 02.catarrhini     105 86.777%
 03.eukaryota     105 86.777%
 04.haplorhini     105 86.777%
 05.hominidae     105 86.777%
 06.humans     105 86.777%
 07.mammals     105 86.777%
 08.primates     105 86.777%
 09.vertebrates     105 86.777%
 10.chordata     104 85.950%
查看更多
字段:解剖
记录数
占%
 01.心血管系统     28 23.141%
 02.血液     18 14.876%
 03.血清     9 7.438%
 04.     8 6.612%
 05.心脏     7 5.785%
 06.血浆     6 4.959%
 07.体内分泌物     5 4.132%
 08.消化系统     4 3.306%
 09.     4 3.306%
 10.神经系统     4 3.306%
查看更多
字段:食品
记录数
占%
 01.glucose     36 29.752%
 02.phosphorus     31 25.620%
 03.cholesterol     8 6.612%
 04.食品     7 5.785%
 05.total lipid     4 3.306%
 06.fat     3 2.479%
 07.protein     3 2.479%
 08.meals     2 1.653%
 09.alanine     1 0.826%
 10.alcohol     1 0.826%
查看更多
没有聚类出数据
字段:主题词与主题词
记录数
占%
 01.diabetes mellitus, type 2/epidemiology与sleep disorders/epidemiology     4 3.306%
 02.bariatric surgery与obesity, morbid/surgery     3 2.479%
 03.diabetes mellitus, type 2/epidemiology与obesity/epidemiology     3 2.479%
 04.diabetes mellitus, type 2/epidemiology与sleep     3 2.479%
 05.gastroplasty/methods与obesity, morbid/surgery     3 2.479%
 06.blood glucose/metabolism与hemoglobin a, glycosylated/metabolism     2 1.653%
 07.cardiovascular diseases/epidemiology与diabetes mellitus, type 2/epidemiology     2 1.653%
 08.circadian rhythm/physiology与sleep/physiology     2 1.653%
 09.diabetes mellitus, type 2/complications与obesity/complications     2 1.653%
 10.diabetes mellitus, type 2/complications与quality of life     2 1.653%

 

 



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