Neuroinformatics
博文
神经信息学研究进展与信息分析报告
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神经科学和信息科学是当今自然科学研究的两大热点。神经信息学(Neuroinformatics)是这两大学科相结合的新兴边缘学科。其目的是利用现代化信息工具，将不同层次有关脑的研究数据进行分析、处理、整合与建模；建立神经信息学数据库和有关神经系统所有数据的全球知识管理系统．以便从分子水平到整体系统水平研究脑、认识脑、保护脑和开发脑。神经科学家面临的重要问题之一，就是如何灵活有效地管理所有过去和今后研究获得大量有关脑的实验数据和研究结果，最大限度地利用这些实验数据，减少不必要的重复性研究和人力物力的浪费。http://baike.baidu.com/view/1038418.htm
人类脑计划包括神经科学和信息学相互结合的研究，其核心内容是神经信息学。脑科学和信息学是当今国际科学研究的两大热点，神经信息学是这两大学科相结合的新兴的边缘学科。其目标是利用现代化信息工具，使神经科学家和信息学家能够将脑的结构和功能研究结果联系起来，其将不同层次有关脑的研究数据进行检索、比较、分析、整合、建模和仿真，绘制出脑功能、结构和神经网络图谱，从而解决当前神经科学所面临的海量数据问题，从基因到行为各个水平加深人类对大脑的理解，达到“认识脑、保护脑和创造脑”的目标。http://baike.baidu.com/view/95130.htm
2014科研大国投资项目：美国“脑计划”加速 http://it.chinabyte.com/285/12834285.shtml
神经信息学 Neuroinformatics
Publications: 259| Citation Count: 2,010 (Self-Citation: 348)
Year Range: 2003-2011
Year Range: 2003-2011
Fields of study: Neuroscience
http://academic.research.microsoft.com/Journal/8048/neuroinformatics?query=Neuroinformatics
信息分析平台 http://www.pubmedplus.cn/Pubmed/Statistic
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- While much information is available on the structural connectivity of the cerebral cortex, especially in the primate, the main organizational principles of the connection patterns linking brain areas, columns and individual cells have remained elusive. We attempt to characterize a wide variety of cortical connectivity data sets using a specific set of graph theory methods. We measure global aspects of ...
- WebQTL is a website that combines databases of complex traits with fast software for mapping quantitative trait loci (QTLs) and for searching for correlations among traits. WebQTL also includes well-curated genotype data for five sets of mouse recombinant inbred (RI) lines. Thus, to identify QTLs, users need provide only quantitative trait data from one of the supported populations. The ...
- Inferences drawn from functional magnetic resonance imaging (fMRI) studies are dependent on the statistical criteria used to define different brain regions as “active” or “inactive” under the experimental manipulation. In fMRI studies of multisensory integration, additional criteria are used to classify a subset of the active brain regions as “multisensory.” Because there is no general agreement in the literature ...
- Embodied agents (organisms and robots) are situated in specific environments sampled by their sensors and within which they carry out motor activity. Their control architectures or nervous systems attend to and process streams of sensory stimulation, and ultimately generate sequences of motor actions, which in turn affect the selection of information. Thus, sensory input and motor activity are continuously and ...
- Long-range corticocortical connectivity in mammalian brains possesses an intricate, nonrandom organization. Specifically, projections are arranged in ‘small-world’ networks, forming clusters of cortical areas, which are closely linked among each other, but less frequently with areas in other clusters. In order to delineate the structure of cortical clusters and identify their members, we developed a computational approach based on ...
- Biomedical researchers and medical professionals are regularly required to compare a vast quantity of neurodevelopmental literature obtained from an assortment of mammals whose brains grow at diverse rates, including fast developing experimental rodent species and slower developing humans. In this article, we introduce a database-driven website, which was created to address this problem using statistical-based algorithms to integrate ...
- Online retrieval, processing, and visualization of primate connectivity data from the CoCoMac Database (Citations: 47)
Connectivity is the key to understanding distributed and cooperative brain functions. Detailed and comprehensive data on large-scale connectivity between primate brain areas have been collated systematically from published reports of experimental tracing studies. Although the majority of the data have been made easily available for online retrieval, the multiplicity of brain maps and the precise requirements of anatomical naming ... - In this article, we systematically review the current literature on neural connectivity and dynamics, or equivalently, structure and function. In particular, we discuss how changes in the connectivity of a neural network affect the spatiotemporal network dynamics qualitatively. The three major criteria of comparison are, first, the local dynamics at the network nodes which includes fixed point dynamics, oscillatory and ...
- Full genome sequencing, high-density genotyping, expanding sets of microarray assays, and systematic phenotyping of neuroanatomical and behavioral traits are producing a wealth of data on the mouse central nervous system (CNS). These disparate resources are still poorly integrated. One solution is to acquire these data using a common reference population of isogenic lines of mice, providing a point of ...
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