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膀胱癌基因本体信息分析报告

已有 2313 次阅读 2013-10-16 08:21 |个人分类:信息分析|系统分类:科研笔记| 信息, 分析报告, 膀胱癌

       近日，来自乔治城大学医学院等机构的科学家们发现了与膀胱癌相关的基因突变。相关研究论文现已刊登在了近期出版的《自然-遗传学》（Nature Genetics）杂志上。

       研究人员发现 STAG2 是膀胱癌中最常见的突变基因，特别是在非转移性癌症中。研究人员表示，该发现表明检测该基因的状态有助于确定膀胱癌病人的治疗方法。

科学家发现膀胱癌相关基因  http://www.bio360.net/news/show/7429.html


筛选
字段：基因本体(细胞组件)
记录数
占%
01.chromosome    1222 篇2.082%
02.cytoplasm    487 篇0.830%
03.intracellular    485 篇0.826%
04.cell surface    480 篇0.818%
05.host    441 篇0.751%
06.plasma membrane    412 篇0.702%
07.nuclear matrix    256 篇0.436%
08.collagen    242 篇0.412%
09.extracellular matrix    236 篇0.402%
10.chromatin    219 篇0.373%
11.cytoskeleton    203 篇0.346%
12.basement membrane    179 篇0.305%
13.microtubule    157 篇0.267%
14.endoplasmic reticulum    137 篇0.233%
15.nucleolus organizer region    122 篇0.208%
16.plastoglobule    117 篇0.199%
17.intermediate filament    90 篇0.153%
18.m band    82 篇0.140%
19.chromosome, telomeric region    79 篇0.135%
20.peroxisome    67 篇0.114%
21.chromosome, centromeric region    62 篇0.106%
22.x chromosome    42 篇0.072%
23.y chromosome    37 篇0.063%
24.cell wall    36 篇0.061%
25.axon    14 篇0.024%
26.brush border    10 篇0.017%
27.a band    9 篇0.015%
28.neurofilament    8 篇0.014%
29.myelin sheath    7 篇0.012%
30.sex chromatin    5 篇0.009%
31.nadh dehydrogenase complex    3 篇0.005%
32.z disc    2 篇0.003%
33.coated vesicle    1 篇

0.002


筛选
字段：基因本体(分子功能)
记录数
占%
01.deoxyribodipyrimidine photo-lyase activity    974 篇1.659%
02.rna-directed rna polymerase activity    830 篇1.414%
03.ethanolamine-phosphate cytidylyltransferase activity    616 篇1.049%
04.dna binding    394 篇0.671%
05.fibroblast growth factor receptor binding    343 篇0.584%
06.map kinase activity    211 篇0.359%
07.interleukin-2 receptor binding    186 篇0.317%
08.catalytic activity    127 篇0.216%
09.taurine-pyruvate aminotransferase activity    123 篇0.210%
10.interleukin-6 receptor binding    114 篇0.194%
11.insulin-like growth factor receptor binding    88 篇0.150%
12.ubiquitin-protein ligase activity    82 篇0.140%
13.interleukin-1 receptor binding    54 篇0.092%
14.peroxidase activity    36 篇0.061%
15.fibroblast growth factor-activated receptor activity    35 篇0.060%
16.cyclin-dependent protein kinase activity    35 篇0.060%
17.template for synthesis of g-rich strand of telomere dna activity    29 篇0.049%
18.superoxide dismutase activity    26 篇0.044%
19.protein serine/threonine phosphatase activity    9 篇0.015%
20.nitric oxide binding    6 篇0.010%
21.l-aspartate:2-oxoglutarate aminotransferase activity    5 篇0.009%
22.gtpase activity    3 篇0.005%
23.thymidine phosphorylase activity    3 篇0.005%
24.lanosterol synthase activity    1 篇0.002%
25.chloramphenicol o-acetyltransferase activity    1 篇0.002%

筛选
字段：基因本体(生物过程)
记录数
占%
01.growth    4272 篇7.277%
02.developmental process    3919 篇6.676%
03.biosynthetic process    3662 篇6.238%
04.biological regulation    2239 篇3.814%
05.regulation of cell cycle    1660 篇2.828%
06.apoptosis    1588 篇2.705%
07.micturition    1103 篇1.879%
08.behavior    1100 篇1.874%
09.transcription, dna-dependent    1096 篇1.867%
10.cell cycle    1036 篇1.765%
11.cytolysis    948 篇1.615%
12.feeding behavior    900 篇1.533%
13.signaling    815 篇1.388%
14.localization    734 篇1.250%
15.cell growth    666 篇1.135%
16.plant-type hypersensitive response    638 篇1.087%
17.signal transduction    632 篇1.077%
18.angiogenesis    547 篇0.932%
19.catabolic process    325 篇0.554%
20.cell motility    324 篇0.552%
21.aging    264 篇0.450%
22.s phase    252 篇0.429%
23.hypersensitivity    222 篇0.378%
24.translation    218 篇0.371%
25.double-strand break repair via homologous recombination    178 篇0.303%
26.cell cycle arrest    173 篇0.295%
27.tissue development    154 篇0.262%
28.rna interference    146 篇0.249%
29.epithelial to mesenchymal transition    107 篇0.182%
30.interphase    101 篇0.172%
31.homeostatic process    70 篇0.119%
32.m phase    64 篇0.109%
33.female pregnancy    39 篇0.066%
34.embryo development    35 篇0.060%
35.anatomical structure morphogenesis    34 篇0.058%
36.t cell proliferation    12 篇0.020%
37.b cell differentiation    4 篇0.007%
38.neurogenesis    2 篇0.003%
39.b cell proliferation    2 篇0.003%
40.notch signaling pathway    1 篇0.002%
41.t cell differentiation    1 篇0.002%


筛选
字段：基因/蛋白
记录数
占%
01.p53    1374 篇2.341%
02.pt1    855 篇1.457%
03.ras    476 篇0.811%
04.epidermal growth factor    430 篇0.733%
05.ifn    334 篇0.569%
06.cyclin    333 篇0.567%
07.mode    332 篇0.566%
08.p21    303 篇0.516%
09.bcl 2    298 篇0.508%
10.tccs    275 篇0.468%
11.glycoprotein    267 篇0.455%
12.vac    260 篇0.443%
13.egfr    260 篇0.443%
14.phosphatase    237 篇0.404%
15.vegf    229 篇0.390%
16.p16    220 篇0.375%
17.acetyltransferase    217 篇0.370%
18.cea    214 篇0.365%
19.tnf    213 篇0.363%
20.carcinoembryonic antigen    212 篇0.361%
21.glutathione s transferase    212 篇0.361%
22.tumor necrosis factor    209 篇0.356%
23.egf    205 篇0.349%
24.tp53    204 篇0.348%
25.actin    203 篇0.346%
26.pdt    199 篇0.339%
27.fgfr3    199 篇0.339%
28.cox 2    188 篇0.320%
29.peroxidase    188 篇0.320%
30.akt    187 篇0.319%
31.il 2    186 篇0.317%
32.protein kinase    183 篇0.312%
33.nat2    175 篇0.298%
34.ifn gamma    173 篇0.295%
35.embryonic    167 篇0.284%
36.gstm1    166 篇0.283%
37.insulin    161 篇0.274%
38.ppm    155 篇0.264%
39.vimentin    152 篇0.259%
40.matrix protein    150 篇0.256%
41.cd4    147 篇0.250%
42.adm    129 篇0.220%
43.fibronectin    126 篇0.215%
44.tpa    123 篇0.210%
45.gst    122 篇0.208%
46.ha ras    121 篇0.206%
47.il 6    114 篇0.194%
48.p27    108 篇0.184%
49.erk    95 篇0.162%
50.pi3k    81 篇0.138%










数据来源  http://www.pubmedplus.cn/Pubmed/Statistic 
















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