http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/edit_b.cgi

 

Start A-Literature C-Literature B-list Filter Literature

A-query: monotherapy C-query: type 2 diabetes The B-list contains title words and phrases (terms) that appeared in both the A and the C literature. 1154 articles appeared in both literatures and were not included in the process of computing the B-list but can be viewed here. The results of this search are saved under id # 24998 and can be accessed from the start page after you leave this session. There are 1083 terms on the current B-list (298 are predicted to be relevant), which is shown ranked according to predicted relevance. The list can be further trimmed down using the filters listed in the left margin. To assess whether there appears to be a biologically significant relationship between the AB and BC literatures for specific B-terms, please select one or more B-terms and then click the button to view the corresponding AB and BC literatures. Use Ctrl to select multiple B-terms.

 

job id # 24998 started Sun Dec 26 23:08:04 2010
Max_citations: 50000
Stoplist: /var/www/html/arrowsmith_uic/data/stopwords_pubmed
Ngram_max: 3
24998 Search ARROWSMITH A
A_query_raw: monotherapyMon Dec 27 01:19:47 2010

A query = monotherapy started Mon Dec 27 01:19:47 2010
A query resulted in 22672 titles
24998 Search ARROWSMITH C
C_query_raw: type 2 diabetes Mon Dec 27 01:19:58 2010

C: type 2 diabetes 74934

A: pubmed_query_A 22672

AC: ( monotherapy ) AND ( type 2 diabetes ) 1154

C query = type 2 diabetes started Mon Dec 27 01:19:58 2010
C query resulted in 50000 titles
A AND C query resulted in 1154 titles
25562 B-terms ready on Mon Dec 27 01:26:01 2010

Sem_filter:
Genes & Molecular Sequences, and Gene & Protein Names
1083 B-terms left after filter executed Mon Dec 27 02:01:28 2010

B-list on Mon Dec 27 02:12:35 2010
1 adiponectin
2 promoter polymorphism
3 methylenetetrahydrofolate reductase gene
4 toll receptor
5 cyp2c9
6 akt
7 vegf
8 single nucleotide polymorphism
9 mtor
10 ppargamma
11 at1
12 methylenetetrahydrofolate reductase
13 mrsa
14 cyp2c19
15 pi3k
16 ghrelin
17 leptin receptor
18 leptin
19 cd40 ligand
20 amylin
21 erk1
22 rho kinase
23 microrna
24 statin
25 phosphatidylinositol 3-kinase
26 impaired glucose tolerance
27 hdl
28 angiotensin system gene
29 angiotensin receptor
30 apoa5
31 glycogen synthase
32 drb1
33 cyp2d6
34 visfatin
35 hla drb1
36 ppar
37 protein kinase b
38 cd133
39 body mass index
40 e selectin
41 nephrin
42 promoter polymorphism associated
43 hfe gene
44 metabolic syndrome
45 hmg coa reductase
46 receptor tyrosine kinase
47 apolipoprotein e
48 dmsa
49 cholesterol absorption
50 ctla-4
51 platelet activation
52 rbp4
53 ccr5
54 g polymorphism
55 candidate gene
56 pcos
57 histone deacetylase
58 il-6
59 pten
60 il-18
61 ppar gamma
62 bone mineral density
63 apolipoprotein b
64 ppar alpha
65 fabp2 gene
66 polycystic ovary syndrome
67 gene promoter
68 caspase
69 fk506
70 alpha2b
71 enzyme gene
72 p selectin
73 microsatellite
74 diabetic nephropathy
75 oxide synthase gene
76 transcription factor
77 cd40
78 microsatellite polymorphism
79 angiopoietin-2
80 hrt
81 adiposity
82 egfr
83 stat5
84 autophagy
85 glycogen synthase kinase
86 aromatase
87 tyrosine kinase
88 stat3
89 igf
90 reductase gene
91 fabp2
92 cyclin dependent kinase
93 hyperinsulinemia
94 cannabinoid receptor
95 paraoxonase
96 cetp
97 alpha adducin gene
98 p38
99 proinsulin
100 caspase-8
101 hyperlipidemia
102 angiotensinogen gene
103 alfa
104 map kinase
105 vitamin d receptor
106 hypercholesterolemia
107 pcsk9
108 systolic blood pressure
109 angiotensin receptor gene
110 copd
111 calcium channel
112 tnf alpha
113 lkb1
114 bdnf
115 ldl
116 ts-1
117 il-1beta
118 alanine aminotransferase
119 iga nephropathy
120 polymorphism gene
121 vcam-1
122 th1
123 ptca
124 peroxisome
125 nph
126 brca1
127 body mass
128 shr
129 matrix metalloproteinase
130 chop
131 signal regulated kinase
132 cd40l
133 capd
134 ctgf
135 alt
136 multiple endocrine neoplasia
137 renin
138 il-12
139 endothelin
140 p300
141 hdl cholesterol level
142 arb
143 ish
144 apoe
145 triglyceride level
146 hfe
147 cyp3a4
148 tnfalpha
149 qtc
150 nf kappab
151 receptor gene
152 interleukin receptor
153 promoter genotype
154 toll
155 genome wide
156 icam-1
157 lean
158 combination renin angiotensin
159 p53 gene
160 gene associated
161 igf i
162 xr
163 ssri
164 gamma glutamyltransferase
165 tnf
166 paraoxonase arylesterase
167 cd28
168 glucose transporter
169 epidermal growth factor
170 cytokine
171 ace
172 peptide yy
173 aldosterone system gene
174 angiopoietin
175 il-10
176 transporter gene
177 mek
178 fdg
179 apoc3
180 bcl xl
181 chemokine
182 natriuretic peptide gene
183 islet
184 angiotensinogen
185 insulin level
186 estrogen receptor beta
187 hiv
188 estrogen receptor alpha
189 epoxide hydrolase
190 tumor necrosis factor
191 trail
192 cytokine gene
193 bcl-2
194 epilepsy
195 gt g
196 allele
197 cox-2
198 proteinuria
199 diabetes mellitus
200 foxp3
201 snap-25
202 protein tyrosine kinase
203 cytosolic phospholipase a2
204 gad
205 vitamin e c
206 promoter
207 smad
208 adrenomedullin
209 aminotransferase
210 gene cluster
211 sonic hedgehog
212 insulin growth factor
213 chromatin remodeling
214 cd34
215 troponin
216 hepatocyte growth factor
217 il-4
218 acat
219 transporter
220 eotaxin
221 gene variant
222 triglyceride
223 apolipoprotein a
224 immediate early gene
225 il-1
226 promoter human
227 dopamine receptor
228 hcc
229 cd8
230 protein kinase
231 cd25
232 interferon alpha
233 alpha2a
234 hyperparathyroidism
235 interleukin-10 gene
236 3'-untranslated region
237 e deficient mice
238 tp53
239 her-2
240 iiia
241 glut1
242 obese
243 cpg
244 lipase
245 promoter region
246 han
247 src
248 cxcr4
249 vitiligo
250 atherosclerosis
251 beta gene
252 exon
253 prostate cancer
254 ifn alpha
255 inflammatory bowel disease
256 erk
257 th2
258 diabetes
259 hbe
260 alzheimer disease
261 lh
262 nadph oxidase
263 ret
264 chd
265 cytokine production
266 cpap
267 enhancer
268 il-8
269 ctla4
270 p glycoprotein
271 tgf beta
272 gpcr
273 cyclin
274 epic
275 apoprotein
276 guar
277 atg
278 orofacial cleft
279 foxo3a
280 sun
281 ifn gamma
282 il-1ra
283 virus genome
284 blood glucose level
285 glycoprotein iiia gene
286 codon
287 extracellular matrix gene
288 bp
289 cml
290 interleukin
291 genome
292 bypass
293 pbx1
294 obesity
295 protein kinase c
296 ciii
297 paget disease bone
298 early gene

http://arrowsmith.psych.uic.edu/cgi-bin/arrowsmith_uic/show_sentences.cgi

 

Start A-Literature C-Literature B-list Filter Literature

AB literature   B-term   BC literature   monotherapy cyp2c9 type 2 diabetes 1: Influence of CYP2C9 polymorphism on metabolism of valproate and its hepatotoxin metabolite in Iranian patients. 2010 Add to clipboard 2: Effects of CYP2C19 and CYP2C9 genotypes on pharmacokinetic variability of valproic acid in Chinese epileptic patients: nonlinear mixed-effect modeling. 2009 Add to clipboard 3: Effect of CYP2D6 and CYP2C9 genotypes on fluoxetine and norfluoxetine plasma concentrations during steady-state conditions. 2004 Add to clipboard 4: Relationship between haloperidol plasma concentration, debrisoquine metabolic ratio, CYP2D6 and CYP2C9 genotypes in psychiatric patients. 2004 Add to clipboard 5: QTc interval, CYP2D6 and CYP2C9 genotypes and risperidone plasma concentrations. 2004 Add to clipboard 6: Thioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype. 2003 Add to clipboard   1: Loss-of-function CYP2C9 variants: finding the correct clinical role for Type 2 diabetes pharmacogenetic testing. 2010 Add to clipboard 2: Analysis of CYP2C9*2, CYP2C19*2, and CYP2D6*4 polymorphisms in patientswith type 2 diabetes mellitus. 2010 Add to clipboard 3: Effect of CYP2C9 polymorphisms on prescribed dose and time-to-stable dose of sulfonylureas in primary care patients with Type 2 diabetes mellitus. 2010 Add to clipboard 4: Presence of CYP2C9*3 allele increases risk for hypoglycemia in Type 2 diabetic patients treated with sulfonylureas. 2009 Add to clipboard 5: Effect of CYP2C9 genetic polymorphisms on the efficacy and pharmacokinetics of glimepiride in subjects with type 2 diabetes. 2006 Add to clipboard 6: Association between CYP2C9 slow metabolizer genotypes and severe hypoglycaemia on medication with sulphonylurea hypoglycaemic agents. 2005 Add to clipboard

 

 

 

 

 

 

转载本文请联系原作者获取授权，同时请注明本文来自许培扬科学网博客。
链接地址：https://wap.sciencenet.cn/blog-280034-397987.html

上一篇：今日临床证据 EvidenceUpdates: This month's most accessed arti
下一篇：组蛋白脱乙酰基酶抑制剂与白血病研究的基因知识发现