美国遗传学家。1995年与艾瑞克·威斯乔斯和克里斯汀·纽斯林-沃尔哈德共享诺贝尔生理医学奖。爱德华·路易斯（英语：Edward B. Lewis，1918年5月20日－2004年7月21日）

https://baike.baidu.com/item/%E7%88%B1%E5%BE%B7%E5%8D%8E%C2%B7%E8%B7%AF%E6%98%93%E6%96%AF/9556778?fromModule=lemma_inlink

https://pubmed.ncbi.nlm.nih.gov/10731135/

summary-LewisEB-set.txt

Abstract

The sequence of the Drosophila melanogaster genome presented in this issue of Science is the latest milestone in nine decades of research on this organism. Genetic and physical mapping, whole-genome mutational screens, and functional alteration of the genome by gene transfer were pioneered in metazoans with the use of this small fruit fly. Here we look at some of the instances in which work on Drosophila has led to major conceptual or technical breakthroughs in our understanding of animal genomes.

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Publication types

• Historical Article

• Portrait

• Research Support, U.S. Gov't, P.H.S.

MeSH terms

• Animals

• Animals, Genetically Modified

• Chromosome Mapping / history

• Cloning, Molecular

• Computational Biology / history

• Drosophila melanogaster / genetics*

• Genes, Insect

• Genetics / history*

• Genome*

• History, 20th Century

• Mutation

• Nobel Prize

• Physical Chromosome Mapping / history

• Recombination, Genetic

• Sequence Analysis, DNA

Related information

• Cited in Books

• MedGen

Grant support

• HD06331/HD/NICHD NIH HHS/United States

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