博文
韩春雨论文撤稿 国内外反响强烈
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Retracted online 02 August 2017We are retracting our study because of the continued inability of the research community to replicate the key results in Figure 4, using the protocols provided in our paper. In this figure we report that the Natronobacterium gregoryi Argonaute can efficiently create double-strand breaks and edit the genome of human cells using 5ʹ phosphorylated single-stranded DNA as a guide. Despite the efforts of many laboratories (Protein Cell 7, 913–915, 2016; Nat. Biotechnol. 35, 17–18, 2017; Cell Res. 26, 1349–1352, 2016; PLOS One 12, e0177444, 2017), an independent replication of these results has not been reported. We are therefore retracting our initial report at this time to maintain the integrity of the scientific record. We nevertheless continue to investigate the reasons for this lack of reproducibility with the aim of providing an optimized protocol.
https://www.nature.com/nbt/journal/v34/n7/full/nbt.3547.html
韩春雨论文8月2日撤稿 替代计量得分为385分
http://blog.sciencenet.cn/blog-280034-1069263.html
533分 8月7日
https://nature.altmetric.com/details/7114638/news
今天为524分，说明撤稿效应很大，反响强烈。
https://nature.altmetric.com/details/7114638
519分
https://www.nature.com/nbt/journal/v34/n7/nbt.3547/metrics
国际媒体对NgAgo论文被撤的反应
http://blog.sciencenet.cn/blog-39731-1069550.html
韩春雨的论文撤了 学术界争论依旧
http://news.sciencenet.cn/htmlnews/2017/8/384264.shtm
中华医学会杂志社副社长刘冰表示，学术期刊撤稿原因有很多，比如经同行验证发现内容存在明显错误，内容抄袭等学术不端行为等。对论文内容真实性和科学性的判定，不是期刊出版者一己之力能完成的，论文发表后等于自动提交给同行进行审视，这本身就是学术共同体的自我净化机制。越是国际大刊，撤稿频率越高。如截至2012年，《自然》撤稿70篇。
http://www.sohu.com/a/162225044_464387
在国内外学者几番公开质疑其可重复性过去一年后，河北科技大学副教授韩春雨关于新基因编辑技术NgAgo-gDNA的论文已由《自然-生物技术》撤回。 韩春雨。资料图 北京时间8月3日，《自然-生物技术》发表题为《是该数据说话的时候了》社论（原文链接），并宣布撤回韩… 北京时间8月3日，《自然-生物技术》发表题为《是该数据说话的时候了》社论，并宣布撤回韩春雨团队于2016年5月2日发表在该期刊的论文。澎湃新闻此前便已获悉，论文撤回，是韩春雨主动申请撤回。《自然-生物技术》在社论中表示：“我们现在确信韩春雨的撤稿决定是维护已… 原标题：韩春雨NgAgo论文被自然子刊撤稿：系作者主动申请撤回澎湃新闻记者 王盈颖 杨漾在国内外学者几番公开质疑其可重复性过去一年后，河北科技大学副教授韩春雨关于新基因编辑技术NgAgo-gDNA的论 原标题：韩春雨NgAgo论文被自然子刊撤稿：系作者主动申… Yesterday [Autonomous] systems can be used in a variety of ways. A vehicle is only one, but there are many different areas of it. In der Gentechnik wachsen die Bäume wieder in den Himmel. Ein Jahrzehnt nach dem Humangenomprojekt – bei dem die Erwartungen an… 5 dicembre 2016 - - Stampa Presentata a maggio, NgAgo sembrava un’alternativa più precisa ed economica a Crispr, tecnica che… (foto: Mina De La O/) Per ora è una rivoluzione in potenza, perché la nuova genetica di precisione promessa da Crispr-Cas9 deve… In a new paper, a team of some 20 researchers says that they were unable to replicate a proposed alternative to the CRISPR/Cas9… 今天，由国内外二十家实验室负责人联名撰写的一篇名为“Questions about NgAgo”的文章在Protein Cell杂志上发表，提出无法重复韩春雨的NgAgo实验，将针对韩春雨的NgAgo技术的争论推入了一个新的阶段。这二十家实验室都来自于中外知… 本文转载自公众号“醉心科学”（ID： zuixinkexue） 今天，由国内外二十家实验室负责人联名撰写的一篇名为“Questions about NgAgo”的文章在Protein Cell杂志上发表，提出无法重复韩春雨的NgAgo实验，将针对韩春雨的Ng… 本文转载自公众号“醉心科学”（ID： zuixinkexue） 今天，由国内外二十家实验室负责人联名撰写的一篇名为“Questions about NgAgo”的文章在Protein Cell杂志上发表（Burgess et al。， 2016，点击链接查看… Nonostante i successi ottenuti in questi anni, la popolare tecnica di editing genetico ha alcune limitazioni che hanno indotto… Nonostante i successi ottenuti in questi anni, la popolare tecnica di editing genetico ha alcune limitazioni che hanno indotto… Home Other Sciences Other August 15, 2016 August 15, 2016 by Tabitha M. Powledge, Plos Blogs It was, potentially, "the most… Courtesy Han Chunyu Biologist Han Chunyu receives dozens of harassing calls and texts each day, but he is convinced that his… NEW YORK (GenomeWeb) – A newly proposed genome-editing platform based on a bacterial Argonaute protein is drawing significant… A Chinese scientist has discovered a genome-editing technique that has the potential to help bald men regain their hair. Han Chunyu (sitting) introduces his scientific finding to journalists from China Youth Daily. RNA 导向的核酸内切酶Cas9使得基因编辑成为了一种广泛应用的技术。然而，尽管科学家们已尝试多种方式对Cas9系统进行优化以提高它的效率和特异性，但该系统的实用性依然受到了一些因素的限制，包括其对导向-靶向（guide–target）错配的耐受性以及导向R…
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