3月10日，《Science》以封面专题的形式，发表 7 篇文章介绍了世界上首个人工再造的真核生命体。这是继合成原核生物染色体之后的又一里程碑式突破，有望开启人类“设计生命、再造生命和重塑生命”的新纪元。其中，天津大学化工学院系统生物工程教育部重点实验室元英进团队参与了这项国际合作，同清华大学、华大基因的研究人员一起，完成了大部分成果。

近期，元英进教授为期刊Frontiers of Chemical Science of Engineering组织了一期专辑《合成生物学进展》，来自中国、美国、日本、英国、新加坡、韩国的专家们分别介绍了自己的最新研究成果，内容值得关注。文章列表如下：

Editorial

Collaborations of China with the world in Synbio

Yingjin Yuan, Jinchuan Wu, Xiao Wang

REVIEW ARTICLE

Synthetically engineered microbes reveal interesting principles of cooperation

Michael D. Dressler, Corey J. Clark, Chelsea A. Thachettu, Yasmine Zakaria, Omar Tonsi Eldakar, Robert P. Smith

Genetic biosensors for small-molecule products: Design and applications in high-throughput screening

Qingzhuo Wang, Shuang-Yan Tang, Sheng Yang

Rhamnolipid synthesis and production with diverse resources

Qingxin Li

Genome reprogramming for synthetic biology

Kylie Standage-Beier, Xiao Wang

Cell surface protein engineering for high-performance whole-cell catalysts

Hajime Nakatani, Katsutoshi Hori

Cell-free systems in the new age of synthetic biology

Fernando Villarreal, Cheemeng Tan

Cofactor engineering in cyanobacteria to overcome imbalance between NADPH and NADH: A mini review

Jongmoon Park, Yunnam Choi

RESEARCH ARTICLE

Identification of transporter proteins for PQQ-secretion pathways by transcriptomics and proteomics analysis in Gluconobacter oxydans WSH-003

Hui Wan, Yu Xia, Jianghua Li, Zhen Kang, Jingwen Zhou

Engineering of β-carotene hydroxylase and ketolase for astaxanthin overproduction in Saccharomyces cerevisiae

Ruizhao Wang, Xiaoli Gu, Mingdong Yao, Caihui Pan, Hong Liu, Wenhai Xiao, Ying Wang, Yingjin Yuan

Optimization and modeling of biohydrogen production by mixed bacterial cultures from raw cassava starch

Shaojie Wang, Zhihong Ma, Ting Zhang, Meidan Bao, Haijia Su

Construction, characterization and application of a genome-wide promoter library in Saccharomyces cerevisiae

Ting Yuan, Yakun Guo, Junkai Dong, Tianyi Li, Tong Zhou, Kaiwen Sun, Mei Zhang, Qingyu Wu, Zhen Xie, Yizhi Cai, Limin Cao, Junbiao Dai

Profiling influences of gene overexpression on heterologous resveratrol production in Saccharomyces cerevisiae

Duo Liu, Bingzhi Li, Hong Liu, Xuejiao Guo, Yingjin Yuan

COMMUNICATION

Assembly of biosynthetic pathways in Saccharomyces cerevisiae using a marker recyclable integrative plasmid toolbox

Lidan Ye, Xiaomei Lv, Hongwei Yu

Production of rhamnolipids-producing enzymes of Pseudomonas in E. coli and structural characterization

Kata Kiss, Wei Ting Ng, Qingxin Li

VIEWS & COMMENTS

Designer enzyme for green materials innovation: Lactate-polymerizing enzyme as a key catalyst

Seiichi Taguchi

Frontiers of Chemical Science and Engineering是2007年创刊出版的全英文化学科学与工程领域国际综合性学术刊物，由教育部主管、高等教育出版社、中国工程院与天津大学联合主办，德国Springer公司海外发行，以网络版和印刷版两种形式出版。主编为天津大学王静康院士、中科院兰州化学物理研究所薛群基院士和中国石油化工集团公司曹湘洪院士。该刊重点刊登反映当前化学科学与工程领域热点的优秀学术论文及综述，以快捷方式发表最新研究成果。涉及化学科学与工程的所有领域，主要包括：催化及反应工程，清洁能源，功能材料，纳米科学与技术，生物材料和技术，颗粒技术和多相过程，分离科学与技术，可持续技术和绿色过程等。

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期刊主页 http://link.springer.com/journal/11705

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